Stabilized Low-n Amyloid-β Oligomers Induce Robust Novel Object Recognition Deficits Associated with Inflammatory, Synaptic, and GABAergic Dysfunction in the Rat-Reference-Cited by-同舟云学术

Stabilized Low-n Amyloid-β Oligomers Induce Robust Novel Object Recognition Deficits Associated with Inflammatory, Synaptic, and GABAergic Dysfunction in the Rat

Published:2018-02-06 Issue:1 Volume:62 Page:213-226
ISSN:1387-2877
Container-title:Journal of Alzheimer's Disease
language:
Short-container-title:JAD

Author:

Watremez William¹,Jackson Joshua¹,Almari Bushra¹,McLean Samantha L.²,Grayson Ben¹,Neill Joanna C.¹,Fischer Nicolas³,Allouche Ahmad³,Koziel Violette³,Pillot Thierry³,Harte Michael K.¹

Affiliation:

1. Division of Pharmacy and Optometry, University of Manchester, Manchester, UK

2. School of Pharmacy and Medical Sciences, University of Bradford, Bradford, UK

3. SynAging, Institut Polytechnique National de Lorraine, Vandoeuvre-lès-Nancy, France

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

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3. Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway;Shankar;J Neurosci,2007