Treatment of oromandibular dystonia with botulinum toxin A improves apnea in a teenager with quadriplegic cerebral palsy: A case report

Author:

Roberts Jeremy1,Tenaglia Amy2,Bellissimo Elisabeth2,Kim Heakyung3

Affiliation:

1. Children’s Hospital Colorado, Aurora, CO, USA

2. Columbia University Irving Medical Center, NewYork-Presbyterian Hospital, New York, NY, USA

3. University of Texas Southwestern Medical Center, Dallas, TX, USA

Abstract

This report describes a 15-year-old female with known spastic and dystonic quadriplegic cerebral palsy (CP), Gross Motor Function Classification System IV, and obstructive sleep apnea (OSA). She experienced decreased apneic episodes after receiving onabotulinumtoxin A (BoNT-A) injections for the treatment of oromandibular dystonia (OMD). After her OSA diagnosis, she initially received injections to the bilateral masseter and temporalis muscles with no effect on the frequency of nightly apneic episodes. Subsequently, the bilateral lateral pterygoid muscles were added and she was later noted to have fewer apneic episodes overnight. This case report describes the use of BoNT-A in the muscles of mastication for management of OMD and the ensuing improvement in OSA in a teenager with CP.

Publisher

IOS Press

Subject

Rehabilitation,Physical Therapy, Sports Therapy and Rehabilitation,Pediatrics, Perinatology and Child Health

Reference7 articles.

1. Gross Motor Function Classification System (GMFCS). Allambie Heights, New South Wales, Australia: Cerebral Palsy Alliance [updated 2018; cited 2022 Feb 17], Available from: https://cerebralpalsy.org.au/our-research/about-cerebral-palsy/what-is-cerebral-palsy/severity-of-cerebral-palsy/gross-motor-function-classification-system/

2. Dystonia in Cerebral Palsy. Milwaukee: American Academy for Cerebral Palsy and Developmental Medicine; 2016 [cited 2022 Feb 17], Available from: https://www.aacpdm.org/publications/care-pathways/dystonia-in-cerebral-palsy

3. Respiratory problems in children with neurological impairment;Seddon;Arch Dis Child,2003

4. Sleep abnormalities in patients with severe cerebral palsy;Kotagal;Dev Med Child Neurol,1994

5. An evidence-based review of botulinum toxin (Botox) applications in non-cosmetic head and neck conditions;Persaud;JRSM Short Rep,2013

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3