Pharmaceutical plant machine availability prediction using Artificial Neural Network

Abstract

During the 2nd phase of COVID-19 pandemic, pharmaceutical plant industry is facing lot of production pressure and machine availability plays vital role in maximizing the manufacturing pharmacy product output. In this paper, Artificial Neural Networks (ANNs) based information processing algorithm has been used to provide a solution to this problem and it has been found suitable to predict machines availability as a prediction function. The considered pharmaceutical plants are dealing with production of medicines related common symptoms in case of COVID-19 (fever, coughing, and breathing problems). The pharmaceutical plant data corresponding to different values of repair and failure rates of different subsystems is collected from plant and analyzed with the help of validated neural network value of availability. This configuration of ANNs approach developed in this research allowed simplifying computational complexities of conventional approaches to solve a large plant machines availability problem. The ANNs methodology in the paper permitted making no assumption, no explicit coding of the problem, no complete knowledge of system configuration, only raw input and clean data found to be sufficient to determine the value of machine availability function for different value of failure and repair rates considered in the paper. The results obtained in the paper are useful for the plant leadership, as the value of failure and repair rates of various subsystems can be fine-tuned at a require clear-cut level to achieve higher availability, and avoid considerably loss of production, loss of man power, and by-pass complete breakdown of concerned system.