The COVID-19 Data Exchange Platform of the German University Medicine

Author:

Prokosch Hans-Ulrich1,Bahls Thomas2,Bialke Martin2,Eils Jürgen3,Fegeler Christian4,Gruendner Julian1,Haarbrandt Birger5,Hampf Christopher2,Hoffmann Wolfgang2,Hund Hauke4,Kampf Marvin6,Kapsner Lorenz A.6,Kasprzak Piotr7,Kohlbacher Oliver8910,Krefting Dagmar11,Mang Jonathan M.6,Marschollek Michael5,Mate Sebastian6,Müller Armin3,Prasser Fabian3,Sass Julian3,Semler Sebastian12,Stenzhorn Holger813,Thun Sylvia3,Zenker Sven14,Eils Roland3

Affiliation:

1. Chair of Medical Informatics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

2. Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany

3. Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany

4. GECKO Institute, Heilbronn University of Applied Sciences, Heilbronn, Germany

5. Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School, Hannover, Germany

6. Medical Center for Information and Communication Technology, Universitätsklinikum Erlangen, Erlangen, Germany

7. Gesellschaft für wissenschaftliche Datenverarbeitung mbH, Göttingen, Germany

8. Institute for Translational Bioinformatics, University Medical Center, Tübingen, Germany

9. Institute for Bioinformatics and Medical Informatics, University of Tübingen, Tübingen, Germany

10. Department of Computer Science, University of Tübingen, Tübingen, Germany

11. Department of Medical Informatics, University Medical Center Göttingen, Göttingen, Germany

12. TMF – Technology, Methods, and Infrastructure for Networked Medical Research, Berlin, Germany

13. Institute for Medical Biometry, Epidemiology und Medical Informatics, Saarland University Medical Center, Homburg, Germany

14. Staff Unit for Scientific & Medical Technology Development & Coordination (MWTek), Commercial Directorate; Institute for Medical Biometry, Informatics & Epidemiology; Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany

Abstract

COVID-19 has challenged the healthcare systems worldwide. To quickly identify successful diagnostic and therapeutic approaches large data sharing approaches are inevitable. Though organizational clinical data are abundant, many of them are available only in isolated silos and largely inaccessible to external researchers. To overcome and tackle this challenge the university medicine network (comprising all 36 German university hospitals) has been founded in April 2020 to coordinate COVID-19 action plans, diagnostic and therapeutic strategies and collaborative research activities. 13 projects were initiated from which the CODEX project, aiming at the development of a Germany-wide Covid-19 Data Exchange Platform, is presented in this publication. We illustrate the conceptual design, the stepwise development and deployment, first results and the current status.

Publisher

IOS Press

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