Activation of Macrophages and Microglia by Interferon–γ and Lipopolysaccharide Increases Methylglyoxal Production: A New Mechanism in the Development of Vascular Complications and Cognitive Decline in Type 2 Diabetes Mellitus?

Author:

Dhananjayan Karthik1,Gunawardena Dhanushka1,Hearn Nerissa2,Sonntag Tanja2,Moran Chris3,Gyengesi Erika1,Srikanth Velandai3,Münch Gerald124

Affiliation:

1. Department of Pharmacology, School of Medicine, Western Sydney University, Penrith, NSW, Australia

2. Molecular Medicine Research Group, Western Sydney University, Penrith, NSW, Australia

3. Department of Medicine, Peninsula Health & Peninsula Clinical School, Monash University, VIC, Australia

4. National Institute of Complementary Medicine, Western Sydney University, Penrith, NSW, Australia

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

Reference171 articles.

1. Type 2 diabetes as a risk factor for dementia in women compared with men: A pooled analysis of 2.3 million people comprising more than 100,000 cases of dementia;Chatterjee;Diabetes Care,2016

2. The association of diabetes and dementia and possible implications for nondiabetic populations;Ravona-Springer;Expert Rev Neurother,2011

3. Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study;Peila;Diabetes,2002

4. Diabetes mellitus and the risk of dementia: The Rotterdam Study;Ott;Neurology,1999

5. Increased risk of type 2 diabetes in Alzheimer disease;Janson;Diabetes,2004

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