Cascaded layer-coalescing convolution network for brain tumor segmentation

Abstract

Accurate segmentation of brain tumor regions from magnetic resonance images continues to be one of the active topics of research due to the high usability levels of the automation process. Faster processing helps clinicians in identification at initial stage of tumor and hence saves valuable time taken for manual image analysis. This work proposes a Cascaded Layer-Coalescing (CLC) model using convolution neural networks for brain tumor segmentation. The process includes three layers of convolution networks, each with cascading inputs from the previous layer and provides multiple outputs segmenting complete, core and enhancing tumor regions. The initial layer identifies complete tumor, coalesces the discriminative features and the input data, and passes it to the core tumor detection layer. The core tumor detection layer in- turn passes discriminative features to the enhancing tumor identification layer. The information injection through data coalescing voxels results in enhanced predictions and also in effective handling of data imbalance, which is a major contributor in model viewpoint. Experiments were performed with Brain Tumor Segmentation (BraTS) 2015 data. A comparison with existing literature works indicate improvements up to35% in sensitivity, 27% in PPV and 28% in Dice Score, indicating improvement in the segmentation process.