Application of Process Mining for Modelling Small Cell Lung Cancer Prognosis

Author:

Marzano Luca1,Meijer Sebastiaan1,Dan Asaf2,Tendler Salomon2,De Petris Luigi2,Lewensohn Rolf2,Raghothama Jayanth1,Darwich Adam S.1

Affiliation:

1. Division of Health Informatics and Logistics, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), KTH Royal Institute of Technology, Huddinge, Sweden

2. Department of Oncology-Pathology, Karolinska Institutet and the Thoracic Oncology Center, Karolinska University Hospital, Stockholm, Sweden

Abstract

Process mining is a relatively new method that connects data science and process modelling. In the past years a series of applications with health care production data have been presented in process discovery, conformance check and system enhancement. In this paper we apply process mining on clinical oncological data with the purpose of studying survival outcomes and chemotherapy treatment decision in a real-world cohort of small cell lung cancer patients treated at Karolinska University Hospital (Stockholm, Sweden). The results highlighted the potential role of process mining in oncology to study prognosis and survival outcomes with longitudinal models directly extracted from clinical data derived from healthcare.

Publisher

IOS Press

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