Cognitive Impairment Is a Common Comorbidity in Deceased COVID-19 Patients: A Hospital-Based Retrospective Cohort Study

Author:

Martín-Jiménez Paloma1,Muñoz-García Mariana I.1,Seoane David1,Roca-Rodríguez Lucas1,García-Reyne Ana2,Lalueza Antonio234,Maestro Guillermo2,Folgueira Dolores35,Blanco-Palmero Víctor A.146,Herrero-San Martín Alejandro146,Llamas-Velasco Sara146,Pérez-Martínez David A.1346,González-Sánchez Marta146,Villarejo-Galende Alberto1346

Affiliation:

1. Department of Neurology, Hospital Universitario 12 de Octubre, Madrid, Spain

2. Department of Internal Medicine, Hospital Universitario 12 de Octubre, Madrid, Spain

3. Department of Medicine, School of Medicine, Complutense University, Madrid, Spain

4. Group of Neuro degenerative Diseases, Instituto de Investigación Hospital 12 deOctubre (I+12), Madrid, Spain

5. Department of Microbiology, Hospital Universitario 12 de Octubre, Madrid, Spain

6. Biomedical Research Networking Center in Neurodegenerative diseases (CIBERNED), Madrid, Spain

Abstract

We analyzed the frequency of cognitive impairment (CI) in deceased COVID-19 patients at a tertiary hospital in Spain. Among the 477 adult cases who died after admission from March 1 to March 31, 2020, 281 had confirmed COVID-19. CI (21.1% dementia and 8.9% mild cognitive impairment) was a common comorbidity. Subjects with CI were older, tended to live in nursing homes, had shorter time from symptom onset to death, and were rarely admitted to the ICU, receiving palliative care more often. CI is a frequent comorbidity in deceased COVID-19 subjects and is associated with differences in care.

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

Reference24 articles.

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2. European Centre for Disease Prevention and Control, Rapid risk assessment: Novel coronavirus disease 2019 (COVID-19) pandemic: increased transmission in the EU/EEA and the UK – sixth update, Last updated March 12, 2020, Accessed on March 12, 2020.

3. Dementia care during COVID-19;Wang;Lancet,2020

4. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study;Zhou;Lancet,2020

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