1. Geriatric Unit & Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
2. Department of Geriatrics Center for Aging Brain, Memory Unit, University of Bari, Bari, Italy
3. Casa Sollievo della Sofferenza-Mendel Institute, Rome, Italy and Department of Experimental Medicine and Pathology, University “La Sapienza”, Rome, Italy
4. National Institute on Aging, Longitudinal Studies Section, Harbor Hospital Center, Baltimore, MD, USA