Expression Profiling of Cytokine, Cholinergic Markers, and Amyloid-β Deposition in the APPSWE/PS1dE9 Mouse Model of Alzheimer’s Disease Pathology

Author:

Reale Marcella1,D’Angelo Chiara1,Costantini Erica1,Di Nicola Marta1,Yarla Nagnedra Sastry2,Kamal Mohammad Amjad345,Salvador Nieves6,Perry George7

Affiliation:

1. Department of Medical, Oral and Biotechnological Sciences, University “G. D’Annunzio”, Chieti, Italy

2. Department of Physiology, Divisions of Chemistry and Biochemistry, Pharmacology and Neuroscience, City University of New York Medical School, New York, NY, USA

3. King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia

4. Enzymoics, Hebersham, NSW, Australia

5. Novel Global Community Educational Foundation, Australia

6. Department of Molecular, Cellular and Developmental Neurobiology, Instituto Cajal-CSIC, Madrid, Spain

7. Department of Biology, College of Sciences, The University of Texas at San Antonio, San Antonio, TX, USA

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

Reference60 articles.

1. Relationship between inflammatory mediators, Aβ levels and ApoE genotype in Alzheimer disease;Reale;Curr Alzheimer Res,2012

2. Selective acetyl- and butyrylcholinesterase inhibitors reduce amyloid-β ex vivo activation of peripheral chemo-cytokines from Alzheimer’s disease subjects: exploring the cholinergic anti-inflammatory pathway;Reale;Curr Alzheimer Res,2014

3. Cytokines in neuroinflammation and Alzheimer’s disease;Cacquevel;Curr Drug Targets,2004

4. Inflammation and Alzheimer’s disease;Akiyama;Neurobiol Aging,2000

5. Aβ and inflammatory stimulus activate diverse signaling pathways in monocytic cells: Implications in retaining phagocytosis in Aβ-laden environment;Ekaterina;Front Cell Neurosci,2016

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