Erythromyeloid-Derived TREM2: A Major Determinant of Alzheimer’s Disease Pathology in Down Syndrome

Author:

Raha-Chowdhury Ruma12,Henderson James W.1,Raha Animesh Alexander1,Stott Simon R.W.1,Vuono Romina1,Foscarin Simona1,Wilson Liam2,Annus Tiina2,Fincham Robert3,Allinson Kieren3,Devalia Vinod4,Friedland Robert P.5,Holland Anthony2,Zaman Shahid H.2

Affiliation:

1. Department of Clinical Neuroscience, John Van Geest Centre for Brain Repair, Cambridge, UK

2. Department of Psychiatry, Cambridge Intellectual and Developmental Disabilities Research Group, University of Cambridge, Cambridge, UK

3. Clinical Pathology, Addenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

4. Department of Haematology, Luton and Dunstable Hospital NHS Foundation Trust, Luton, UK

5. University of Louisville School of Medicine, Louisville, KY, USA

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

Reference68 articles.

1. Alzheimer’s disease and Down’s syndrome;Mann;Histopathology,1988

2. Alzheimer’s disease in Down syndrome;Head;Eur J Neurodegener Dis,2012

3. Early age-related progression of AD-like neuropathology in Down’s syndrome;Sparks;Am J Neurodegener Dis,2013

4. Down’s syndrome and the links with Alzheimer’s disease;Holland;J Neurol Neurosurg Psychiatry,1995

5. The pathological association between Down syndrome and Alzheimer disease;Mann;Mech Ageing Dev,1988

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