Post-Traumatic Stress Disorder and Risk of Parkinson’s Disease in a Veteran Cohort-Reference-Cited by-同舟云学术

Post-Traumatic Stress Disorder and Risk of Parkinson’s Disease in a Veteran Cohort

Published:2024-09-03 Issue:6 Volume:14 Page:1265-1269
ISSN:1877-7171
Container-title:Journal of Parkinson's Disease
language:
Short-container-title:JPD

Author:

Weaver Frances M.¹²,Cao Lishan¹,Stroupe Kevin T.¹²,Gonzalez Beverly³,Brown Ethan⁴,Colletta Kalea⁵,Tanner Caroline M.⁴⁶,Goldman Samuel M.⁷⁶

Affiliation:

1. Center of Innovation for Complex Chronic Healthcare (CINCCH), Edward Hines Jr. VA Hospital, Hines, IL, USA

2. Parkinson School of Health Sciences and Public Health, Loyola University, Maywood, IL, USA

3. Cooperative Studies Coordinating Center, Edward Hines Jr. VA Hospital, Hines, IL, USA

4. Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA

5. Neurology Service, Edward Hines Jr. VA Hospital, Hines, IL, USA

6. Research Service, San Francisco VA Health Care System, San Francisco, CA, USA

7. Division of Occupational, Environmental, and Climate Medicine, University of California, San Francisco, San Francisco, CA, USA

Abstract

Post-traumatic stress disorder (PTSD) may be a risk factor for Parkinson’s disease (PD). We examined the relation between PTSD and PD in a cohort of 158,122 Veterans who had any Veterans Health Administration (VHA) or Medicare health care utilization between 10/1/1999– 2/17/2021. Using a nested case-control design we matched 10 controls to each Veteran with PD by sex, race, and rank. In conditional logistic regression models adjusted for camp and smoking, a PTSD diagnosis was significantly associated with PD (OR = 1.35; p = 0.0002); odds were higher if PTSD was coded before PD (OR = 1.53, p < 0.0001). PTSD may be a risk factor for PD.

Publisher

IOS Press

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