Prevalence and Safety of COVID-19 Vaccination in Community-Dwelling People with Dementia: Findings from a Tertiary Memory Clinic in Italy

Author:

Valletta Martina1,Canevelli Marco12,D’Antonio Fabrizia1,Trebbastoni Alessandro1,Talarico Giuseppina1,Campanelli Alessandra1,Sepe Monti Micaela1,Di Vita Antonella1,Salati Emanuela1,Imbriano Letizia1,Margiotta Roberta1,Barbetti Sonia1,Diana Sofia1,Buscarnera Simona1,Toccaceli Blasi Marco1,Salzillo Martina1,Pugliese Giuseppe1,Vanacore Nicola2,Bruno Giuseppe1

Affiliation:

1. Department of Human Neuroscience, “Sapienza” University, Rome, Italy

2. National Center for Disease Prevention and Health Promotion, National Institute of Health, Rome, Italy

Abstract

This study aimed to explore the prevalence and safety of SARS-CoV-2 vaccination in individuals with dementia. Patients with mild cognitive impairment or dementia were recruited at a tertiary memory clinic, from March 15 to September 15, 2021. Information on COVID-19 vaccination and adverse events experienced after vaccine administration were collected from caregivers. Two-hundred-seventy subjects were finally recruited. Among them, 253 (93.7%) had received the vaccine and only 69 (27.3%) experienced adverse events. Cognitive and behavioral changes following immunization were only rarely reported. COVID-19 vaccination is safe and well-tolerated in patients with cognitive impairment who should be prioritized in the vaccination campaign.

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

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