1. Roche Pharma Research and Early Development (pRED), Roche Innovation Center, F. Hoffmann-La Roche Ltd., Basel, Switzerland
2. Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
3. Institute for Neurodegenerative Disorders, New Haven, CT, USA
4. Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
5. Roche Product Development, F. Hoffmann La Roche Ltd., Basel, Switzerland
6. University of Exeter Medical School, London, UK