Mild Cognitive Impairment is Associated with Poorer Everyday Decision Making

Author:

Fenton Laura1,Han S. Duke12345,DiGuiseppi Carolyn G.6,Fowler Nicole R.7,Hill Linda8,Johnson Rachel L.9,Peterson Ryan A.9,Knoepke Christopher E.1011,Matlock Daniel D.101213,Moran Ryan8,Karlawish Jason14,Betz Marian E.1512

Affiliation:

1. Department of Psychology, USC Dornsife College of Letters, Arts, and Sciences, Los Angeles, CA, USA

2. Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, IL, USA

3. Department of Family Medicine, Keck School of Medicine of USC, Alhambra, CA, USA

4. Department of Medicine, Keck School of Medicine of USC, Los Angeles, CA, USA

5. Department of Neurology, Keck School of Medicine of USC, Los Angeles, CA, USA

6. Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA

7. Center for Aging Research, Indiana University School of Medicine, Regenstrief Institute, Indianapolis, IN, USA

8. School of Public Health, University of California San Diego, San Diego, CA, USA

9. Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA

10. Adult & Child Consortium for Outcomes Research & Delivery Science, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA

11. Division of Cardiology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA

12. VA Eastern Colorado Geriatric Research Education and Clinical Center, Aurora, CO, USA

13. Division of Geriatric Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO, USA

14. Penn Memory Center, Departments of Medicine, Medical Ethics and Health Policy, and Neurology, University of Pennsylvania, Philadelphia, PA, USA

15. Department of Emergency Medicine, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA

Abstract

Background: Older adults are faced with many unique and highly consequential decisions such as those related to finances, healthcare, and everyday functioning (e.g., driving cessation). Given the significant impact of these decisions on independence, wellbeing, and safety, an understanding of how cognitive impairment may impact decision making in older age is important. Objective: To examine the impact of mild cognitive impairment (MCI) on responses to a modified version of the Short Portable Assessment of Capacity for Everyday Decision making (SPACED). Methods: Participants were community-dwelling, actively driving older adults (N = 301; M age = 77.1 years, SD = 5.1; 69.4% with a college degree or higher; 51.2% female; 95.3% White) enrolled in the Advancing Understanding of Transportation Options (AUTO) study. A generalized linear model adjusted for age, education, sex, randomization group, cognitive assessment method, and study site was used to examine the relationship between MCI status and decision making. Results: MCI status was associated with poorer decision making; participants with MCI missed an average of 2.17 times more points on the SPACED than those without MCI (adjusted mean ratio: 2.17, 95% CI: 1.02, 4.61, p = 0.044). Conclusion: This finding supports the idea that older adults with MCI exhibit poorer decision-making abilities than cognitively normal older adults. It also suggests that older adults with MCI may exhibit poorer decision making across a wide range of decision contexts.

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

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