Failure to Recover from Proactive Semantic Interference and Abnormal Limbic Connectivity in Asymptomatic, Middle-Aged Offspring of Patients with Late-Onset Alzheimer’s Disease

Author:

Sánchez Stella M.123,Abulafia Carolina124,Duarte-Abritta Barbara1,de Guevara M. Soledad Ladrón12,Castro Mariana N.125,Drucaroff Lucas125,Sevlever Gustavo6,Nemeroff Charles B.7,Vigo Daniel E.24,Loewenstein David A.7,Villarreal Mirta F.123,Guinjoan Salvador M.1258

Affiliation:

1. Service of Psychiatry, FLENI Foundation, Buenos Aires, Argentina

2. National Council for Scientific and Technological Research (CONICET), Argentina

3. Department of Physics (FCEyN), University of Buenos Aires, Argentina

4. Institute for Biomedical Research (BIOMED), Pontifical Catholic University of Argentina, and The National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina

5. Department of Psychiatry and Mental Health, University of Buenos Aires School of Medicine, Argentina

6. Department of Neuropathology and Molecular Biology, FLENI Foundation, Buenos Aires, Argentina

7. Department of Psychiatry and Behavioral Sciences and Center on Aging, Miller School of Medicine, University of Miami, Miami, FL, USA

8. Neurophysiology I, University of Buenos Aires School of Psychology, Argentina

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

Reference37 articles.

1. Preclinical Alzheimer’s disease:Definition, natural history, and diagnostic criteria;Dubois;Alzheimers Dement,2016

2. Über eine eigenartige Erkrankung derHirnrinde;Alzheimer;Allg Zschr Psychiatr Psych Gerichtl Med,1907

3. Alzheimer’s disease: The amyloid cascade hypothesis;Hardy;Science,1992

4. Alzheimer’s diseasedrug-development pipeline: Few candidates, frequent failures;Cummings;Alzheimers Res Ther,2014

5. Neuropathological stageing of Alzheimer-related changes;Braak;Acta Neuropathol,1991

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