Author:
Yin Liang,Zhao Xin-Xiu,Gao Shun-Li,Yuan Wen-Ling,Wu Ke,Qian Wei-Dong,Li Qian-Qian
Abstract
BACKGROUND: Vascular tortuosity is a prevalent morphological change that frequently occurs in arteries across different parts of the body. OBJECTIVE: To analyze the relationship between the tortuosities of the extracranial internal carotid artery (EICA) and extracranial vertebral artery (EVA) with mild cognitive impairment. METHODS: The tortuosity index (TI), vascular deviation degree, tortuosity degree, and angle number of the EICA and EVA were retrospectively analyzed and calculated in 160 patients who underwent computed tomography angiography (CTA) in this study’s department, and the Montreal cognitive assessment was adopted to evaluate the cognitive function of the patients. RESULTS: The differences in age, gender, arterial hypertension (AH), and diabetes mellitus (DM) between the normal group and the mild cognitive impairment group were statistically significant (p< 0.01). The TI was negatively correlated with the score of cognitive function. The tortuosities of the EICA and EVA were correlated with mild cognitive impairment (p< 0.05). The reduction in visual-spatial ability was correlated with the right EICA tortuosity, and the reduction in memory was correlated with the EVA tortuosity. Age, gender, HP, DM, and coronary heart disease (CHD) were potential risk factors for carotid tortuosity (p< 0.05). CONCLUSION: There was a significant correlation observed between the TIs of both the EICA and EVA and the presence of mild cognitive impairment. Advanced age, female, HP, DM, and CHD were independent risk factors for EICA and EVA tortuosities.
Subject
Health Informatics,Biomedical Engineering,Information Systems,Biomaterials,Bioengineering,Biophysics
Reference28 articles.
1. Computational simulations of the helical buckling behavior of blood vessels;Sharzehee;International Journal for Numerical Methods in Biomedical Engineering.,2019
2. Asymptomatic carotid artery stenosis is associated with cerebral hypoperfusion
3. GP6 promotes the development of cerebral ischemic stroke induced by atherosclerosis via the FYN-PKA-pPTK2/FAK1 signaling pathway;Gu;Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University.,2021
4. Study on the correlation of neck artery tortuosity and cognitive dysfunction;Yin;Journal of Bengbu Medical College.,2018
5. Kinking of bilateral internal carotid arteries as cause of cognitive dysfunction;Amidzic;Medical Archives (Sarajevo, Bosnia and Herzegovina).,2020