Striatal Cholesterol Precursors Are Altered with Age in Female Huntington’s Disease Model Mice

Author:

Pfalzer Anna C.12,Wages Phillip A.34,Porter Ned A.3456,Bowman Aaron B.12768

Affiliation:

1. Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA

2. Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA

3. Department of Chemistry, Vanderbilt University, Nashville, TN, USA

4. Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN, USA

5. Vanderbilt Kennedy Center for Research on Human Development, Vanderbilt University, Nashville, TN, USA

6. Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA

7. Vanderbilt Center in Molecular Toxicology, Vanderbilt University Medical Center, Nashville, TN, USA

8. School of Health Sciences, Purdue University, West Lafayette, IN, USA

Publisher

IOS Press

Subject

Cellular and Molecular Neuroscience,Clinical Neurology

Reference52 articles.

1. Intracellular cholesterol trafficking and impact in neurodegeneration;Arenas;Front Mol Neurosci,2017

2. Brain cholesterol: Long secret life behind a barrier;Bjorkhem;Arterioscler Thromb Vasc Biol,2004

3. Marked differences in cholesterol synthesis between neurons and glial cells from postnatal rats;Nieweg;J Neurochem,2009

4. Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways;Mitsche;Elife,2015

5. Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington’s disease;Valenza;Neurobiol Dis,2007

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