DIBI, a polymeric hydroxypyridinone iron chelator, reduces ocular inflammation in local and systemic endotoxin-induced uveitis

Author:

Arora N.1,Caldwell A.234,Wafa K.2,Szczesniak A.3,Caldwell M.3,Al-Banna N.2,Sharawy N.2,Islam S.2,Zhou J.2,Holbein B.E.15,Kelly M.E.M.23,Lehmann Ch.1234

Affiliation:

1. Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada

2. Department of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, Halifax, NS, Canada

3. Department of Pharmacology, Dalhousie University, Halifax, NS, Canada

4. Department of Physiology and Biophysics, Dalhousie University, Halifax, NS, Canada

5. Chelation Partners Inc, Halifax, NS, Canada

Publisher

IOS Press

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Hematology,Physiology

Reference34 articles.

1. Causes and frequency of blindness in patients with intraocular inflammatory disease;Rothova;Br J Ophthalmol,1996

2. The Standardization of Uveitis Nomenclature (SUN) project: Development of a clinical evidence base utilizing informatics tools and techniques;Trusko;Methods Inf Med,2013

3. Immunosuppressive Treatment of Non-infectious Uveitis: History and Current Choices;Chan;Chinese Med Sci J = Chung-Kuo I Hsueh K’o Hsueh Tsa Chih,2017

4. Intravitreal sustained-release dexamethasone device in the treatment of experimental uveitis;Jaffe;Ophthalmology,1994

5. The gold standard of noninfectious uveitis: Corticosteroids. New Treat;LeHoang;Noninfectious Uveitis,2012

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