Dogs with Cognitive Dysfunction as a Spontaneous Model for Early Alzheimer’s Disease: A Translational Study of Neuropathological and Inflammatory Markers

Author:

Schütt Trine12,Helboe Lone2,Pedersen Lars Østergaard3,Waldemar Gunhild4,Berendt Mette1,Pedersen Jan Torleif2

Affiliation:

1. Department of Veterinary Clinical and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark

2. Department of Neurodegeneration, H. Lundbeck A/S, Valby, Denmark

3. Department of Biologics, H. Lundbeck A/S, Valby, Denmark

4. Danish Dementia Research Centre, Rigshospitalet, University of Copenhagen, Denmark

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

Reference87 articles.

1. The canine as a model of human cognitive aging: Recent developments;Adams;Prog Neuro-Psychopharmacol Biol Psychiatry,2000

2. The canine as an animal model of human aging and dementia;Cummings;Neurobiol Aging,1996

3. Cognitive dysfunction syndrome: A disease of canine and feline brain aging;Landsberg;Vet Clin North Am Small Anim Pract,2012

4. Cognitive function, progression of age-related behavioral changes, biomarkers, and survival in dogs more than 8 years old;Schutt;J Vet Intern Med,2015

5. Davis PR , Head E (2014) Prevention approaches in a preclinical canine model of Alzheimer’s disease: Benefits and challenges. Front Pharmacol 5, Article 47.

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