Non-Phosphorylated Tau as a Potential Biomarker of Alzheimer’s Disease: Analytical and Diagnostic Characterization

Author:

Lewczuk Piotr12,Lelental Natalia1,Lachmann Ingolf3,Holzer Max4,Flach Katharina3,Brandner Sebastian5,Engelborghs Sebastiaan6,Teunissen Charlotte E.7,Zetterberg Henrik89,Molinuevo José Luis10,Mroczko Barbara2,Blennow Kaj8,Popp Julius11,Parnetti Lucilla12,Chiasserini Davide12,Perret-Liaudet Armand13,Spitzer Philipp1,Maler Juan Manuel1,Kornhuber Johannes1

Affiliation:

1. Department of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen, and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

2. Department of Neurodegeneration Diagnostics, Medical University of Białystok, and Department of Biochemical Diagnostics, University Hospital of Białystok, Białystok, Poland

3. AJ Roboscreen GmbH, Leipzig, Germany

4. Paul Flechsig Institute of Brain Research, University of Leipzig, Germany

5. Department of Neurosurgery, Universitätsklinikum Erlangen, and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

6. Reference Center for Biological Markers of Dementia (BIODEM), Institute Born-Bunge, University of Antwerp, Antwerp, and Department of Neurology and Memory Clinic, Hospital Network Antwerp (ZNA) Middelheim and Hoge Beuken, Antwerp, Belgium

7. Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands

8. Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden

9. Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK

10. Alzheimer’s Disease and Other Cognitive Disorders Unit, Hospital Clinic, IDIBAPS, Barcelona, Spain

11. Service of Old Age Psychiatry, Department of Psychiatry, University Hospital of Lausanne, Switzerland

12. Laboratory of Clinical Neurochemistry, Department of Medicine, Section of Neurology, University of Perugia, Perugia, Italy

13. Hospices Civils de Lyon, Groupement Hospitalier Est, Biochemistry Department, Neurochemistry unit; Lyon University, Lyon Neuroscience Research Center, INSERM U1028, CNRS UMR 5292, BioRaN Team, Bron Cedex, France

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

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