Affiliation:
1. Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy
Abstract
BACKGROUND: In the last years cardiovascular risk has decreased in grown adults and elderly while it seems to be rising among young adults. OBJECTIVE: to assess the 10-year cardiovascular risk (CVR) in young healthcare professionals at the teaching hospital in Rome, using two scores, and identify possible determinants in order to design and implement preventive strategies. METHODS: A cross-sectional study was carried out between January 2019 and July 2020. Participants underwent medical history collection, physical examination, and blood tests. CVR was calculated using CUORE and Framingham Risk Scores. A multiple linear regression analysis was conducted having the scores as dependent variables. Diagnostic tests were used for checking model assumptions. RESULTS: The study was carried out including 525 participants, 58.5% physicians and 32.1% nurses. Multivariate analysis was carried out only for men, since the pp plot for the whole population and for females for the dependent variables showed some evidence of non-normality, and the residual plot shows variance of the residuals was not constant across the range of fitted values. CVR, using the Framingham equation, directly correlated with age (β = 0.260; p < 0.001). Using the CUORE score, qualification as a physician (p < 0.001) is associated with a lower risk of having a CVR, while age (p < 0.001) is directly proportional to this risk. CONCLUSIONS: Increasing age consistently emerges as a prominent factor, positively influencing both the Framingham risk score and CUORE score, but this association was found only for men. Being a doctor is a protective factor for the CUORE score.
Reference40 articles.
1. Evaluation of cardiovascular risk profile: A comparative analysis between CUORE algorithm and the Framingham risk scores;la Torre;Eur Rev Med Pharmacol Sci,2018
2. Contributions of treatment and lifestyle to declining CVD mortality: Why have CVD mortality rates declined so much since the 1960s?;O’Flaherty;Heart,2013
3. Challenges and opportunities for the prevention and treatment of cardiovascular disease among young adults: Report from a national heart, lung, and blood institute working group;Gooding;Journal of the American Heart Association. American Heart Association Inc.
4. Twenty Year Trends and Sex Differences in Young Adults Hospitalized with Acute Myocardial Infarction: The ARIC Community Surveillance Study;Arora;Circulation,2019