Affiliation:
1. School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China
Abstract
BACKGROUND: Cardiac cine magnetic resonance (CCMR) imaging plays an important role in the clinical cardiovascular disease (CVD) examination and evaluation. OBJECTIVE: To accurately reconstruct the displacement field and describe the motion of the left ventricular myocardium (LVM), this study proposes and tests a new approach for tracking myocardial motion of the left ventricle based on a biomechanical model. METHODS: CCMR imaging data acquired from 103 patients are enrolled, including two simulated and 101 clinical data. A non-rigid image registration method with a combination of a thin-plate spline function and random sample consensus is used to recover the observed displacement field of LVM. Next, a biomechanical model and a material matrix are introduced to solve the dense displacement field of LVM using a finite element framework. Then, the tracking precision and error of results for the two groups are analyzed. RESULTS: Displacement results of the simulated data show correlation coefficient≥0.876 and mean square error≤0.159, while displacement results of the clinical data show Dice≥0.97 and mean contour distance≤0.464. Additionally, the strain results show correlation coefficient≥0.717. CONCLUSIONS: This study demonstrates that the proposed new method enables to accurately track the motion of the LVM and evaluate strain, which has clinical auxiliary value in the diagnosis of CVD.
Subject
Electrical and Electronic Engineering,Condensed Matter Physics,Radiology, Nuclear Medicine and imaging,Instrumentation,Radiation
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