A Safety and Immunogenicity Study of a Single Dose of a Meningococcal (Groups A, C, W, and Y) Polysaccharide Diphtheria Toxoid Conjugate Vaccine (MEN-ACWY-D) in Healthy Japanese Participants

Author:

Fukushima Shinji1,Kikuchi Hitoshi2,Miyazu Mitsunobu2,Hamada Atsuo1,Ouchi Kazunobu3,Takagi Hiroki4,Mihara Hanako4,Sasaki Toru4,Oka Hayato4,Bosch-Castells Valerie5,Oster Philipp5

Affiliation:

1. Tokyo Medical University Hospital

2. Meitetsu Hospital

3. Kawasaki Medical School

4. Sanofi K. K.

5. Sanofi Pasteur

Publisher

Editorial Committee of Japanese Journal of Infectious Diseases, National Institute of Infectious Dis

Subject

Infectious Diseases,Microbiology (medical),General Medicine

Reference31 articles.

1. 1. National Institute of Infectious Diseases and Tuberculosis and Infectious Diseases Control Division, Ministry of Health, Labour and Welfare, Japan. Meningococcal infection, 2005-October 2013, Japan. Infect Agents Surveillance Rep. 2013;34:361'-2'.

2. 2. National Institute of Infectious Diseases and Tuberculosis and Infectious Diseases Control Division, Ministry of Health, Labour and Welfare, Japan. Trends in invasive meningococcal disease, week 13, 2013 to week 52, 2014, Japan. Infectious Agents Surveillance Report. 2015;36:179-81. Japanese.

3. 3. Harrison LH. Prospects for vaccine prevention of meningococcal infection. Clin Microbiol Rev. 2006;19:142-64.

4. 4. Keyserling H, Papa T, Koranyi K, et al. Safety, immunogenicity, and immune memory of a novel meningococcal (groups A, C, Y, and W-135) polysaccharide diphtheria toxoid conjugate vaccine (MCV-4) in healthy adolescents. Arch Pediatr Adolesc Med. 2005;159:907-13.

5. 5. Pichichero M, Papa T, Blatter M, et al. Immune memory in children previously vaccinated with an experimental quadrivalent meningococcal polysaccharide diphtheria toxoid conjugate vaccine. Pediatr Infect Dis J. 2006;25:995-1000.

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