Lambda-Interferons Inhibit Herpes Simplex Virus Type 2 Replication in Human Cervical Epithelial Cells by Activating the JAK/STAT Pathway

Author:

Li Zhu12,Lu Xuan1,Zhu Yufan1,Cheng Pengfei1,Liu Shi1,Zhang Yi3,Tang Jingfeng3,Yang Sijun4,Zhou Li14

Affiliation:

1. Wuhan University School of Basic Medical Sciences

2. Army 95377, PLA

3. College of Biological Engineering, Hubei University of Technology

4. Animal Biosafety Level III Laboratory at the Center for Animal Experiment, State Key Laboratory of Virology, Wuhan University

Publisher

Editorial Committee of Japanese Journal of Infectious Diseases, National Institute of Infectious Dis

Subject

Infectious Diseases,Microbiology (medical),General Medicine

Reference40 articles.

1. 1. Kotenko SV, Gallagher G, Baurin VV, et al. IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. Nat Immunol. 2003;4:69-77.

2. 2. Prokunina-Olsson L, Muchmore B, Tang W, et al. A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus. Nat Genet. 2013;45:164-71.

3. 3. Uze G, Monneron D. IL-28 and IL-29: newcomers to the interferon family. Biochimie. 2007;89:729-34.

4. 4. Sheppard P, Kindsvogel W, Xu W, et al. IL-28, IL-29 and their class II cytokine receptor IL-28R. Nat immunol. 2003;4:63-8.

5. 5. Hou W, Wang X, Ye L, et al. Lambda interferon inhibits human immunodeficiency virus type 1 infection of macrophages. J Virol. 2009;83:3834-42.

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