COMPARATIVE STUDIES ON THE VIRULENCE OF TWO SUBSTRAINS (H2Rv AND H2Ra) DISSOCIATED FROM A STRAIN OF VIRULENT TUBERCLE BACILLI (H2) BY SINGLE CELL CULTIVATION

Author:

KATSUYAMA SHIGERU,KANAI KOOMI

Publisher

Editorial Committee of Japanese Journal of Infectious Diseases, National Institute of Infectious Dis

Subject

General Biochemistry, Genetics and Molecular Biology

Reference9 articles.

1. BLOCH, H. & SEGAL, W. (1955) : Viability and multiplication of vaccines in immunization against tuberculosis. Am. Rev. Tuberc., 71, 228-248.

2. CORN, M. L., KOVITZ, C., ODA, U. & MIDDLEBROOK, G. (1954) : Studies on isoniazid and tubercle bacilli. 2. The growth requirements, catalase activities, and pathogenic properties of isoniazid resistant mutants. Am. Rev. Tuberc., 70, 641-664.

3. KANAI, K. & YANAGISAWA, K. (1955) : Studies on the reinfection in experimental tuberculosis of guinea pigs. Jap. J. M. Sc. & Biol., 8, 115-127.

4. KANAI, K., KATSUYAMA, S. & YANAGISAWA, K. (1955) : An interference phenomenon between virulent and avirulent tubercle bacilli concerning their multiplication and survival in guinea pigs, with special reference to the mechanism of virulence-enhancement of mycobacterial strains by animal passage. Jap. J. M. Sc. & Biol., 8, 207-218.

5. KATSUYAMA, S. & KANAI, K. (1958) : Dissociation of strain of tubercle bacilli by single cell cultivation for virulence study. Jap. J. M. Sc. & Biol., 11, 117-128.

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