Avaliação pré-clínica da interferência do chá de <i>Conocarpus erectus </i>L. (Combretaceae) sobre o perfil hematológico e bioquímico de rotina

Author:

Paz Allane Patricia Santos daORCID,Santos Gisely SantiagoORCID,Vale Michael Eduardo Melo doORCID,Galvão Izabela NascimentoORCID,Silva Lara Gabriele Silva daORCID,Negrão Tamara Ingrid dos SantosORCID,Hamoy MoisesORCID,Mello Vanessa Jóia deORCID,Madeira Lucimar Di Paula dos SantosORCID

Abstract

The Conocarpus erectus L, known as “button mangrove”, is a plant with great ethnopharmacological applicability in diabetes, gastric ulcer, and diarrhea, widely used as a single treatment, or associated with allopathy. Using a preclinical model, the present work evaluated possible alterations in the hematological and biochemical tests of Wistar rats after consumption of lyophilized C. erectus L. tea for 40 days, at the dose traditionally used for digestive disorders. Exposure in repeated doses could not promote significant changes in body mass and routine hematological/biochemical parameters evaluated. Studies with these characteristics promote a greater understanding of the use of traditional medicine, the possible interactions on diagnostic laboratory parameters, and the impact on patient follow-up.

Publisher

Fiocruz - Instituto de Tecnologia em Farmacos

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