Abstract
The medicinal plant Piper aduncumwas segregated in Cuba as P. aduncumsubsp. ossanumand P. aduncumsubsp. aduncum, the latter has not been phytochemically investigated in Cuba. This study aims to compare profiles of non-volatile compounds of the aqueous and ethanolic extracts of Cuban Piper aduncumsubspecies leaves. From both subspecies were prepared a decoction and, an ethanolic extract that yield two fractions. Analysis was performed by UPLC-ESI/QTOF/MS. Standard reference compounds were assessed by comparison with MS data of the plants extracts. Also, tentatively assigned compounds were proposed by matching m/z and fragmentation patterns with P. aduncumpublished compounds. Main compounds in decoction and aqueous ethanolic fraction of both subspecies were characterized as flavon-C-glycosides. Isoorientin was not previously reported in P. aduncum. Oleaginous ethanolic extracts differs among subspecies and peaks are coincident with benzoic acid derivate compounds. Results can serve for quality control of P. aduncumin Cuba.