Metformin-induced mitochondrial reactive oxygen species and host defense mechanisms
Author:
Affiliation:
1. Department of Immunology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Publisher
Okayama Medical Association
Link
https://www.jstage.jst.go.jp/article/joma/136/2/136_63/_pdf
Reference31 articles.
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2. Foretz M, Hebrard S, Leclerc J, Zarrinpashneh E, Soty M, et al. : Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state. J Clin Invest (2010) 120, 2355-2369.
3. Evans JM, Donnelly LA, Emslie-Smith AM, Alessi DR, Morris AD : Metformin and reduced risk of cancer in diabetic patients. BMJ (2005) 330, 1304-1305.
4. Bodmer M, Meier C, Krahenbuhl S, Jick SS, Meier CR: Long-term metformin use is associated with decreased risk of breast cancer. Diabetes Care (2010) 33, 1304-1308.
5. Eikawa S, Nishida M, Mizukami S, Yamazaki C, Nakayama E, et al. : Immune-mediated antitumor effect by type 2 diabetes drug, metformin. Proc Natl Acad Sci USA (2015) 112, 1809-1814.
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