1. R&D Unit, Papworth Hospital NHS Trust, Cambridge, UK, and Department of Public Health and Primary Care, University of Cambridge, Institute of Public Health, Cambridge, UK
2. MRC Biostatistics Unit, Institute of Public Health, Cambridge, UK
3. Department of Public Health and Primary Care, University of Cambridge, Institute of Public Health, Cambridge, UK
4. Lung Defence Unit, Papworth Hospital NHS Trust, Cambridge, UK
5. R&D Unit, Papworth Hospital NHS Trust, Cambridge, UK