Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling

Author:

Zholobak Nadezhda M,Popov Anton L,Shcherbakov Alexander B,Popova Nelly R,Guzyk Mykhailo M,Antonovich Valeriy P,Yegorova Alla V,Scrypynets Yuliya V,Leonenko Inna I,Baranchikov Alexander Ye,Ivanov Vladimir K

Abstract

Luminescent organic dots (O-dots) were synthesized via a one-pot, solvent-free thermolysis of citric acid in urea melt. The influence of the ratio of the precursors and the duration of the process on the properties of the O-dots was established and a mechanism of their formation was hypothesized. The multicolour luminescence tunability and toxicity of synthesized O-dots were extensively studied. The possible applications of O-dots for alive/fixed cell staining and labelling of layer-by-layer polyelectrolyte microcapsules were evaluated.

Publisher

Beilstein Institut

Subject

Electrical and Electronic Engineering,General Physics and Astronomy,General Materials Science

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