Phosphazene-catalyzed desymmetrization of cyclohexadienones by dithiane addition-Reference-Cited by-同舟云学术

Phosphazene-catalyzed desymmetrization of cyclohexadienones by dithiane addition

Published:2017-04-24 Issue: Volume:13 Page:762-767
ISSN:1860-5397
Container-title:Beilstein Journal of Organic Chemistry
language:en
Short-container-title:Beilstein J. Org. Chem.

Author:

Horwitz Matthew A,Massolo Elisabetta,Johnson Jeffrey S

Abstract

We report a desymmetrization of cyclohexadienones by intramolecular conjugate addition of a tethered dithiane nucleophile. Mild reaction conditions allow the formation of diversely functionalized fused bicyclic lactones. The products participate in facially selective additions from the convex surface, leading to allylic alcohol derivatives.

Publisher

Beilstein Institut

Subject

Organic Chemistry

Link

https://www.beilstein-journals.org/bjoc/content/pdf/1860-5397-13-75.pdf

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