Construction of trisubstituted chromone skeletons carrying electron-withdrawing groups via PhIO-mediated dehydrogenation and its application to the synthesis of frutinone A

Author:

Li Qiao,Zhuang Chen,Wang Donghua,Zhang Wei,Jia Rongxuan,Sun Fengxia,Zhang Yilin,Du Yunfei

Abstract

The construction of the biologically interesting chromone skeleton was realized by PhIO-mediated dehydrogenation of chromanones under mild conditions. Interestingly, this method also found application in the synthesis of the naturally occurring frutinone A.

Publisher

Beilstein Institut

Subject

Organic Chemistry

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