Author:
Gulevich Anton V,Koroleva Lyudmila S,Morozova Olga V,Bakhvalova Valentina N,Silnikov Vladimir N,Nenajdenko Valentine G
Abstract
The synthesis of new, artificial ribonucleases containing two amino acid residues connected by an aliphatic linker has been developed. Target molecules were synthesized via a catalytic three-component Ugi reaction from aliphatic diisocyanides. Preliminary investigations proved unspecific nuclease activity of the new compounds towards single-stranded RNA and double-stranded circular DNA.
Cited by
13 articles.
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