Author:
Jin Qiao-Wen,Chai Zhuo,Huang You-Ming,Zou Gang,Zhao Gang
Abstract
A highly enantioselective α-amination of 3-substituted oxindoles with azodicarboxylates catalyzed by amino acids-derived chiral phosphine catalysts is reported. The corresponding products containing a tetrasubstituted carbon center attached to a nitrogen atom at the C-3 position of the oxindole were obtained in high yields and with up to 98% ee.
Cited by
16 articles.
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