Clinical-Scale High-Throughput Analysis of Urinary 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine by Isotope-Dilution Liquid Chromatography–Tandem Mass Spectrometry with On-Line Solid-Phase Extraction
Author:
Affiliation:
1. Departments of Public Health and Occupational Safety and Health, Chung Shan Medical University, Taichung, Taiwan
2. Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Kaohsiung, Taiwan
Abstract
Publisher
Oxford University Press (OUP)
Subject
Biochemistry, medical,Clinical Biochemistry
Link
http://academic.oup.com/clinchem/article-pdf/52/7/1381/32686061/clinchem1381.pdf
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3. Kasai H. Analysis of a form of oxidative DNA damage, 8-hydroxy-2′-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis. Mutat Res1997;387:147-163.
4. Cooke MS, Evans MD, Dove R, Rozalski R, Gackowski D, Siomek A, et al. DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine. Mutat Res2005;574:58-66.
5. Yakushiji H, Maraboeuf F, Takahashi M, Deng ZS, Kawabata S, Nakabeppu Y, et al. Biochemical and physicochemical characterization of normal and variant forms of human MTH1 protein with antimutagenic activity. Mutat Res1997;384:181-194.
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