Epidermal Growth Factor Receptor Inhibitors in Lung Cancer: Smaller or Larger Molecules, Selected or Unselected Populations?

Author:

Hirsch Fred R.1,Bunn Paul A.1

Affiliation:

1. University of Colorado Cancer Center, Aurora, CO

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

Reference16 articles.

1. Erlotinib in Previously Treated Non–Small-Cell Lung Cancer

2. Thatcher N, Chang A, Parikh P, et al: ISEL: A phase III survival study comparing gefitinib (IRESSA) plus best supportive care (BSC) with placebo plus BSC, in patients with advanced non-small-cell lung cancer (NSCLC) who had received one or two prior chemotherapy regimens. Lung Cancer 49:S4,2005, (abstr Pr4)

3. Kim ES, Mauer AM, Tran HT, et al: A phase II study of cetuximab, an epidermal growth factor receptor (EGFR) blocking antibody, in combination with docetaxel in chemotherapy refractory/resistant patients with advanced non-small cell lung cancer: Final report. Proc Am Soc Clin Oncol 22:642s,2003, (abstr 2581)

4. Kelly K, Hanna N, Rosenberg A, et al: A multi-center phase I/II study of cetuximab with paclitaxel and carboplatin in untreated patients with stage IV non-small cell lung cancer. Proc Am Soc Clin Oncol 22:644s,2003, (abstr 2592)

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