CTLA-4 Blockade: Autoimmunity As Treatment

Author:

Kapadia Dilnawaz1,Fong Lawrence1

Affiliation:

1. Department of Medicine, Division of Hematology and Oncology, University of California, San Francisco, San Francisco, CA

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

Reference30 articles.

1. Clonal Expansion Versus Functional Clonal Inactivation: A Costimulatory Signalling Pathway Determines the Outcome of T Cell Antigen Receptor Occupancy

2. Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.

3. Identification of an Alternative CTLA-4 Ligand Costimulatory for T Cell Activation

4. Martin PJ, Ledbetter JA, Morishita Y, et al: A 44 kilodalton cell surface homodimer regulates interleukin 2 production by activated human T lymphocytes. J Immunol 136:3282,1986-3287,

5. Jenkins MK, Taylor PS, Norton SD, et al: CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells. J Immunol 147:2461,1991-2466,

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