Advances in the treatment of cholangiocarcinoma: Effect of online education on clinician knowledge and confidence.

Abstract

302 Background: This study determined whether online continuing medical education could improve the knowledge and confidence of clinicianson the latest developments in the treatment of cholangiocarcinoma (CCA). Methods: A 30-minute online video panel discussion was launched for countries outside the USA in March 2020. Data was collected to June 2020. Educational effect assessed with repeated-pairs pre-/post-activity, where individual participants served as their own control. Three multiple-choice, knowledge questions and one self-efficacy, five-point Likert scale confidence question were analyzed. Chi-squared test assessed pre- to post-activity change (5% significance level, P <.05). Magnitude of change in total number of correct responses overall, and for each question, were determined with Cramer’s V (<.06=Modest, 0.06-0.15=Noticeable, .16-.26=Considerable, >.26=Extensive). Results: 85 oncologists (oncs) and 44 gastroenterologists (gastros) completed pre- and post-activity questions. A considerable educational effect was observed for both oncs (V=.174, P<.0001) and gastros (V=.246, p<.0001) with average % of correct responses increasing from 62 to78% and 47 to 71%, respectively. Clinicians with 3/3 answers correct increased post-activity (11 to 48% for oncs, 28 to 51%, for gastros). Improvements in % of correct responses post-activity were seen for questions on the molecular target for pemigatinib, the subtype of CCA where IDH mutations are detectable, and the need for comprehensive molecular testing at diagnosis of metastatic CCA (relative improvements: 31%, 38%, and 11% for oncs; 155%, 50% and 14%, for gastros). 78% of oncologists’ and 72% of gastros’ responses were improved or reinforced post-activity. 21% of all participants stated they would modify treatment plans. Confidence in incorporating routine broad molecular testing in the treatment of CCA improved post-activity with a total average confidence shift of 25% for oncs and 32% for gastros. Conclusions: This on-demand, online video panel discussion resulted in a considerable education effect. Online medical education is valuable in improving knowledge and confidence, as well as identifying areas of continued educational need.