Overall survival (OS) in patients (pts) with advanced non-small cell lung cancer (NSCLC) harboring common (Del19/L858R) epidermal growth factor receptor mutations (EGFR mut): Pooled analysis of two large open-label phase III studies (LUX-Lung 3 [LL3] and LUX-Lung 6 [LL6]) comparing afatinib with chemotherapy (CT).

Author:

Yang James Chih-Hsin1,Sequist Lecia V.2,Schuler Martin H.3,Mok Tony4,Yamamoto Nobuyuki5,O'Byrne Kenneth John6,Hirsh Vera7,Geater Sarayut Lucien8,Zhou Caicun9,Massey Dan10,Zazulina Victoria10,Wu Yi-Long11

Affiliation:

1. National Taiwan University Hospital, Taipei, Taiwan

2. Massachusetts General Hospital and Harvard Medical School, Boston, MA

3. Department of Medicine (Cancer Research), West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany

4. The Chinese University of Hong Kong, Hong Kong, China

5. Wakayama Medical University, Wakayama, Japan

6. St. James's Hospital, Dublin, Ireland

7. McGill University, Montreal, QC, Canada

8. Prince of Songkla University, Songkhla, Thailand

9. Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China

10. Boehringer Ingelheim Ltd, Bracknell, Berkshire, United Kingdom

11. Guangdong Lung Cancer Institute, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou, China

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

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