Comprehensive Review on the Clinical Impact of Next-Generation Sequencing Tests for the Management of Advanced Cancer-Reference-Cited by-同舟云学术

Comprehensive Review on the Clinical Impact of Next-Generation Sequencing Tests for the Management of Advanced Cancer

Published:2023-06 Issue:7 Volume: Page:
ISSN:2473-4284
Container-title:JCO Precision Oncology
language:en
Short-container-title:JCO Precision Oncology

Author:

Gibbs Sarah N.¹^ORCID,Peneva Desi¹^ORCID,Cuyun Carter Gebra²^ORCID,Palomares Melanie R.²^ORCID,Thakkar Snehal²,Hall David W.²^ORCID,Dalglish Hannah¹^ORCID,Campos Cynthia¹^ORCID,Yermilov Irina¹

Affiliation:

1. Partnership for Health Analytic Research (PHAR), LLC, Beverly Hills, CA

2. Exact Sciences Corporation, Madison, WI

Abstract

PURPOSEThis review summarizes the published evidence on the clinical impact of using next-generation sequencing (NGS) tests to guide management of patients with cancer in the United States.METHODSWe performed a comprehensive literature review to identify recent English language publications that presented progression-free survival (PFS) and overall survival (OS) of patients with advanced cancer receiving NGS testing.RESULTSAmong 6,475 publications identified, 31 evaluated PFS and OS among subgroups of patients who received NGS-informed cancer management. PFS and OS were significantly longer among patients who were matched to targeted treatment in 11 and 16 publications across tumor types, respectively.CONCLUSIONOur review indicates that NGS-informed treatment can have an impact on survival across tumor types.

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

Link

https://ascopubs.org/doi/pdfdirect/10.1200/PO.22.00715

Reference61 articles.

1. Applications and analysis of targeted genomic sequencing in cancer studies

2. American Society of Clinical Oncology Policy Statement Update: Genetic and Genomic Testing for Cancer Susceptibility

3. Next generation sequencing-based gene panel tests for the management of solid tumors

4. Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs

5. Next-generation sequencing: recent applications to the analysis of colorectal cancer

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