Characterization of the Tumor Microenvironment of De Novo Oligometastatic Breast Cancer in a Nationwide Cohort

Author:

Steenbruggen Tessa G.12ORCID,Wolf Denise M.2,Thijssen Bram3,Sanders Joyce4ORCID,Cornelissen Sten5,Salgado Roberto67ORCID,Mittempergher Lorenza8ORCID,Bhaskaran Rajith8,Broeks Annegien5ORCID,Lips Esther H.9,Siesling Sabine1011ORCID,Sonke Gabe S.1ORCID,Horlings Hugo M.4ORCID,van ’t Veer Laura J.2

Affiliation:

1. Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands

2. Department of Laboratory Medicine, University of California, San Francisco, CA

3. Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, the Netherlands

4. Department of Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands

5. Core Facility Molecular Pathology & Biobanking, The Netherlands Cancer Institute, Amsterdam, the Netherlands

6. Department of Pathology, GZA-ZNA Hospitals, Antwerp, Belgium

7. Division of Research, Peter Mac Callum Cancer Centre, Melbourne, VIC, Australia

8. Research and Development, Agendia NV, Amsterdam, the Netherlands

9. Department of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands

10. Department of Research and Development, Netherlands Comprehensive Cancer Organisation, (IKNL), Utrecht, the Netherlands

11. Department of Health Technology and Services Research, Technical Medical Centre, University of Twente, Enschede, the Netherlands

Abstract

Extracellular-matrix features distinguish between long-term versus shorter-term survivors with OligoMBC.

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

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