Value of Serum Human Epidermal Growth Factor Receptor 2 (HER2)/neu Testing for Early Prediction of Response to HER2/neu-Directed Therapies Is Still an Open One and Deserves Further Study in Large Prospective Trials
Author:
Affiliation:
1. Penn State University/Hershey Medical Center, Hershey; Lebanon VAMC, Lebanon, PA
2. Oncogene Science/Siemens HealthCare Diagnostics, Cambridge, MA
3. Medical University of Vienna, Vienna, Austria
Publisher
American Society of Clinical Oncology (ASCO)
Subject
Cancer Research,Oncology
Link
http://ascopubs.org/doi/pdfdirect/10.1200/JCO.2009.23.4674
Reference2 articles.
1. Utility of Serum HER2 Extracellular Domain Assessment in Clinical Decision Making: Pooled Analysis of Four Trials of Trastuzumab in Metastatic Breast Cancer
2. Serum HER-2/neuand relative resistance to trastuzumab-based therapy in patients with metastatic breast cancer
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1. Plasma HER2ECD a promising test for patient prognosis and prediction of response in HER2 positive breast cancer: results of a randomized study - SAKK 22/99;BMC Cancer;2020-02-11
2. An updated evaluation of serum sHER2, CA15.3, and CEA levels as biomarkers for the response of patients with metastatic breast cancer to trastuzumab-based therapies;PLOS ONE;2020-01-07
3. Exploitation of Gene Expression and Cancer Biomarkers in Paving the Path to Era of Personalized Medicine;Genomics, Proteomics & Bioinformatics;2017-08
4. Serum Human Epidermal Growth Factor 2 Extracellular Domain as a Predictive Biomarker for Lapatinib Treatment Efficacy in Patients With Advanced Breast Cancer;Journal of Clinical Oncology;2016-03-20
5. Challenges in the clinical utility of the serum test for HER2 ECD;Biochimica et Biophysica Acta (BBA) - Reviews on Cancer;2012-08
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