Predicting Fluorouracil Toxicity: Can We Finally Do It?
Author:
Affiliation:
1. Mayo Clinic Cancer Center, Rochester, MN
Publisher
American Society of Clinical Oncology (ASCO)
Subject
Cancer Research,Oncology
Link
http://ascopubs.org/doi/pdfdirect/10.1200/JCO.2007.15.5481
Reference23 articles.
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2. Role of Genetic and Nongenetic Factors for Fluorouracil Treatment-Related Severe Toxicity: A Prospective Clinical Trial by the German 5-FU Toxicity Study Group
3. Diasio RB, Johnson MR: Dihydropyrimidine dehydrogenase: Its role in 5-fluorouracil clinical toxicity and tumor resistance. Clin Cancer Res 5:2672,1999-2673,
4. Importance of dihydropyrimidine dehydrogenase (DPD) deficiency in patients exhibiting toxicity following treatment with 5-fluorouracil
5. van Kuilenburg AB, Meinsma R, Zonnenberg BA, et al: Dihydropyrimidinase deficiency and severe 5-fluorouracil toxicity. Clin Cancer Res 9:4363,2003-4367,
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