1. From the Royal Marsden Hospital, Sutton, Surrey; Queen Elizabeth Hospital, Birmingham, United Kingdom; Institut Gustave-Roussy, Villejuif, France; Sarah Cannon Research Institute, Nashville, TN; The University of Texas M.D. Anderson Cancer Center, Houston, TX; Novartis Pharma AG; and Novartis Institutes for BioMedical Research, Oncology, Basel, Switzerland