Exceptional Response to Bromodomain and Extraterminal Domain Inhibitor Therapy With BMS-986158 in BRD4-NUTM1 NUT Carcinoma Harboring a BRD4 Splice Site Mutation

Author:

Cheng Michael L.12ORCID,Huang Yeying3,Luong Nhi3,LoPiccolo Jaclyn12,Nishino Mizuki45ORCID,Sholl Lynette M.3ORCID,Chirieac Lucian R.3ORCID,Santucci Alison D.16ORCID,Rabin Michael S.12,Jänne Pasi A.12ORCID,Coker Shodeinde7ORCID,Diamond Jennifer R.8ORCID,Hilton John9ORCID,Shapiro Geoffrey I.2ORCID,French Christopher A.3

Affiliation:

1. Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA

2. Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

3. Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

4. Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

5. Department of Imaging, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

6. Boston Medical Center, Boston, MA

7. Bristol Myers Squibb, Lawrenceville, NJ

8. University of Colorado Cancer Center, Aurora, CO

9. Division of Medical Oncology, Ottawa Hospital, Ottawa, ON

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

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