In Vivo Imatinib Sensitivity in a Patient With GI Stromal Tumor Bearing a PDGFRA Deletion DIM842-844
Author:
Affiliation:
1. Moores Cancer Center, University of California, San Diego, La Jolla, CA
2. University of Michigan, Ann Arbor, MI
Publisher
American Society of Clinical Oncology (ASCO)
Subject
Cancer Research,Oncology
Link
https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2013.50.0082
Reference7 articles.
1. Phase II trial of neoadjuvant/adjuvant imatinib mesylate (IM) for advanced primary and metastatic/recurrent operable gastrointestinal stromal tumor (GIST): Early results of RTOG 0132/ACRIN 6665
2. PDGFRA Mutations in Gastrointestinal Stromal Tumors: Frequency, Spectrum and In Vitro Sensitivity to Imatinib
3. Gastrointestinal stromal tumours(GISTs) negative for KIT(CD117 antigen) immunoreactivity
4. A great majority of GISTs with PDGFRA mutations represent gastric tumors of low or no malignant potential
5. Differential expression of KIT/PDGFRA mutant isoforms in epithelioid and mixed variants of gastrointestinal stromal tumors depends predominantly on the tumor site
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1. A literature review and database of how the primary KIT/PDGFRA variant of a gastrointestinal stromal tumour predicts for sensitivity to imatinib;Cancer Genetics;2022-11
2. Moving gastrointestinal stromal tumours towards truly personalised precision therapy;The Lancet Oncology;2020-07
3. Imatinib therapy in acute myeloid leukemia with DEK‑NUP214 and FIP1L1‑PDGFRA rearrangement: A case report;Oncology Letters;2020-03-10
4. Genomic aberrations in cell cycle genes predict progression of KIT-mutant gastrointestinal stromal tumors (GISTs);Clinical Sarcoma Research;2019-03-05
5. Diagnosis and Treatment Monitoring of a Patient with Gastrointestinal Stromal Tumor by Next-Generation Sequencing and Droplet Digital Polymerase Chain Reaction Assay of a PDGFRA Mutation in Plasma-Derived Cell-Free Tumor DNA;The Oncologist;2019-01-22
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