Local Therapy for Limited Metastatic Non–Small Cell Lung Cancer: What Are the Options and Is There a Benefit?

Author:

Iyengar Puneeth1,Lau Steven1,Donington Jessica S.1,Suh Robert D.1

Affiliation:

1. From the Department of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX; NYU School of Medicine, New York, NY; Department of Radiological Sciences, Thoracic Imaging and Intervention, and Diagnostic Radiology Education, David Geffen School of Medicine at UCLA, Los Angeles, CA; Department of Radiation Oncology, Harold C. Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX.

Abstract

Distant metastasis is common in non–small cell lung cancer (NSCLC) and typically associated with poor prognosis. Aggressive local therapy including surgery and/or radiation for limited metastatic disease from colorectal cancer and sarcoma is associated with survival benefit and has become part of the standard of care. In this article, we review the literature and ongoing studies concerning surgery, radiation, and radiofrequency ablation for oligometastatic NSCLC.

Publisher

American Society of Clinical Oncology (ASCO)

Subject

General Medicine

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