Guidance Statement for the Management of Febrile Neutropenia in Pediatric Patients Receiving Cancer-Directed Therapy in Central America and the Caribbean

Author:

Melgar Mario1,Reljic Tea2,Barahona Guillermo3,Camacho Kattia4,Chang Alicia1,Contreras Johanny5,Espinoza Darrell6,Estripeaut Dora7,Gamero Mario3,Luque Marco8,Mentor Girlande9,Zacasa Pamela8,Homsi Maysam10,Caniza Miguela A.1011,Kumar Ambuj2,Mukkada Sheena1011

Affiliation:

1. Unidad Nacional de Oncología Pediátrica, Guatemala City, Guatemala

2. Department of Internal Medicine, University of South Florida, Tampa, FL

3. Hospital Nacional de Niños Benjamín Bloom, San Salvador, El Salvador

4. Hospital Nacional de Niños Dr. Carlos Sáenz Herrera, San José, Costa Rica

5. Hospital Infantil Dr Robert Reid Cabral, Santo Domingo, Dominican Republic

6. Hospital Infantil Manuel de Jesus Rivera “La Mascota,” Managua, Nicaragua

7. Hospital del Niño Dr José Renán Esquivel, Panama, Panama

8. Hospital Escuela Universitario, Tegucigalpa, Honduras

9. Hôpital Saint Damien, Tabarre, Haiti

10. Department of Global Pediatric Medicine, St Jude Children’s Research Hospital, Memphis, TN

11. Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, TN

Abstract

PURPOSE Our objective was to provide regionally appropriate, resource-conscious recommendations for the diagnosis and treatment of pediatric patients with febrile neutropenia. METHODS A multinational panel of Central American and Caribbean clinicians who deliver pediatric oncology care prioritized clinically important questions and then used the Grading of Recommendations Assessment, Development and Evaluation methodology to provide recommendations on the selected topics. RESULTS Twenty-two questions and 2 definitions were included in the guideline, which was intended to establish minimum care standards for pediatric patients treated in regional centers. Of all the included studies, 6.9% were conducted in low- and middle-income countries, and no studies were performed in countries represented on the panel. CONCLUSION The panel made recommendations on the basis of existing evidence but identified important gaps in knowledge from the region and from resource-limited settings that may affect the clinical applicability of these recommendations. These deficiencies suggest a research agenda that will enable future guidelines to be more responsive to the local context.

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3