1. From the Department of Surgery, Traumatology, Graduate Institute of Clinical Research, National Taiwan University Hospital and College of Medicine; Laboratory of Molecular and Cellular Toxicology, Institute of Toxicology, College of Medicine; Angiogenesis Research Center, National Taiwan University; Department of Applied Statistics and Information Science, Ming Chuan University, Taipei; and the Institutes of Biomedical Sciences and Molecular Biology, National Chung Hsing University, Taichung, Taiwan